Your browser does not support script
Identifying Explaining Managing Supporting Consultation Video
home | about this site
site map | enhanced glossary
What causes NF1?

page 1 | 2 | 3
Dr. Korf determines that Hannah is the first in her family to have NF1.
Read transcript
See more
Expert Interview
Dr. Korf explains the genetics of the disorder.
Read transcript
See more
Personal Story
Miguel talks about Andres being the first person in the family with the disorder.
Read transcript
See more

NF1 is a hereditary disorder due to an alteration, called a mutation, in the NF1 gene. All people have two copies of every gene, one copy inherited from each parent. The NF1 gene mutation is dominant, meaning only one of the two copies of the gene needs to have the mutation to produce the disorder. A parent with NF1 has a 50% chance of passing the abnormal gene copy to a child. A child who inherits the altered gene will also have the disorder. The Inheritance animation below illustrates how this occurs.