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Identifying Explaining Managing Supporting Consultation Video
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What is NF1?
Dr. Korf and Hannah's parents talk about NF1 and its occurrence.
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Expert Interview
Dr. Korf explains the basics of the disorder.
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"Neurofibromatosis" is a term that encompasses at least two distinct, hereditary disorders caused by abnormality in a gene.

Neurofibromatosis type 1 (NF1) is the more common disorder, affecting about 1 in 4,000 people throughout the world. NF1 is characterized by developmental changes in the nervous system, skin, bones, and other tissues. Its most distinctive features are multiple benign, soft tumors called neurofibromas and patches of skin pigmentation called café-au-lait spots. NF1 can also affect nerves throughout the body, including in the brain and spinal cord.

Neurofibromatosis type 2 (NF2) affects about 1 in 40,000 people and is characterized by the appearance of tumors of the hearing and balance nerve, called vestibular schwannomas, as well as other tumors of the nervous system.

Both NF1 and NF2 are genetically determined disorders, meaning all affected members of a family have the same form of NF. It is possible that other types of NF exist, but this has not yet been firmly established.